Clinical Studies for Chronic Pain

Clinical Studies for Chronic Pain
Diabetic peripheral neuropathy [DPN] is caused by diabetes-related damage to the nerves (neuropathy), mainly in the feet, and sometimes in the legs and the hands. It affects more than 3 million Americans and is leading cause of nerve damage-associated pain (neuropathic pain) worldwide. Currently approved drugs such as gabapentin, pregabalin, and duloxetine provide pain relief […]

Translational Research at the WUPC using Human Neurons

Translational Research at the WUPC using Human Neurons
The Gold Standard: Studies of Human Nociceptors Taking Off Thanks to organ donors, researchers are finding ways to access coveted cells by Stephani Sutherland on 19 Dec 2014 In the wake of failed clinical trials based on animal models, the pain field is facing what seems to be an inescapable conclusion: the success of new […]

Relief from Shingle Pain

Relief from Shingle Pain
Shingles (herpes zoster), an often a very painful disease, is caused by the same virus that causes chickenpox. After you have chickenpox, the virus remains inactive in certain nerves of your body. If the virus becomes active again when you are an adult, you get shingles. Symptoms For some people the nerve pain persists well […]

Light — not pain-killing drugs — used to activate brain’s opioid receptors

Light — not pain-killing drugs — used to activate brain’s opioid receptors
Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body’s pain response. But now, neuroscientists at Washington University School of Medicine in St. Louis have found a way to activate opioid receptors […]