Kharasch Lab

The overall goal of my laboratory’s research is to optimize drug disposition, clinical efficacy, drug safety, and patient satisfaction. A major focus is the basic and clinical pharmacology of analgesics and analgesia, seeking to understand the role of disposition and metabolism in patient response and toxicity. The research is translational, and encompasses laboratory investigations of drug metabolism using human tissues and enzymes, and clinical volunteer and patient studies to confirm and validate laboratory findings. The paradigm is bedside to bench and back.

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